Select a medicationscroll to zoom • drag to pan • double-click to reset
Modeled first-order absorption/elimination curve, normalized to % of peak (Cmax). Educational approximation — not an actual measured serum level.
RECEPTOR / TARGET PROFILE
Illustrative relative target engagement at typical clinical doses, based on known binding-affinity rank order — not measured PET occupancy. Hover a bar for the exact value.
Compare medicationsVIEWscroll to zoom • drag to pan • double-click to reset
Each curve is a modeled first-order absorption/elimination approximation, normalized to its own % of peak (Cmax) — useful for comparing timing (Tmax, half-life), not absolute potency. Dashed lines show a drug's normal curve when another selection is boosting or lowering it; * marks a curve adjusted by an interaction (see notes below).
RECEPTOR / TARGET PROFILE
Illustrative relative target engagement at typical clinical doses, based on known binding-affinity rank order — not measured PET occupancy. Colors match the chart above.
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Every receptor/target used by a medication in this app, what happens under agonism vs antagonism, and which drugs engage it. Click a row to highlight it.
Receptor / Target
Agonism
Antagonism
Associated Medications
Illustrative titration schedule derived from this app's start/usual dosing reference using standard weekly-to-biweekly titration conventions — not a curated per-medication protocol. Always follow current prescribing information and individualize to the patient.
WEIGHT-BASED DOSE ESTIMATE
SWITCHING FROM
SWITCHING TO
General illustrative switching strategy — a cross-taper by default, or a washout period when combining a serotonergic drug with an MAO-B inhibitor would risk serotonin syndrome. Not a substitute for clinical guidelines or individualized judgment.
Approximate dose-equivalency reference for classes with a published equivalence concept (benzodiazepine diazepam-equivalents, antipsychotic chlorpromazine-equivalents, SSRI fluoxetine-equivalents, and rough stimulant conversion). Educational reference only — not a precise clinical dosing calculator; always use clinical judgment and current guidelines.